Conjunctival Melanoma: Insights into Classification, Outcomes, and Biomarkers

Conjunctival melanoma is quite rare, estimated at approximately 0.5/1 million persons/year. This malignancy arises from a pre-existing nevus (7%), primary acquired melanosis (74%), or de novo without pre-existing condition (19%) and develops most often in patients with Fitzpatrick skin types I (23%) and II (62%). At initial presentation, the tumor size is approximately 13 mm in cross-sectional diameter and 3 mm thickness, involving the bulbar (97%), forniceal (30%), tarsal (28%), or caruncular (11%) regions, often with corneal (54%) and rarely with orbital (4%) involvement.

Source: Clinics in Dermatology - October 17, 2023 Category: Dermatology Authors: Carol L. Shields, Ana Maria Velasco Silva, Andrea Laiton, Nicholas E. Kalafatis, Emily Schiller, Sara E. Lally, Jane M. Grant-Kels, Jerry A. Shields Source Type: research