Direct regulation of the cardiac ryanodine receptor (RyR2) by O-GlcNAcylation

O-GlcNAcylation is the enzymatic addition of a sugar, O-linked β-N-Acetylglucosamine, to the serine and threonine residues of proteins, and is abundant in diabetic conditions. We have previously shown that O-G...

Source: Cardiovascular Diabetology - October 13, 2023 Category: Cardiology Authors: Chidinma A Okolo, Ei-Phyo Khaing, Valeria Mereacre, Rachel S Wallace, Michelle L Munro, Jeffrey R Erickson and Peter P. Jones Tags: Research Source Type: research