Proteomic and genomic profiling of plasma exosomes from patients with ankylosing spondylitis

Conclusions
Individuals with AS have different immunological and genetic profiles, as determined by evaluating the exosomes of these patients. The inhibitory effect of exosomes on Treg in AS suggests a mechanism contributing to chronically activated T cells in this disease.

Source: Annals of the Rheumatic Diseases - October 12, 2023 Category: Rheumatology Authors: Tavasolian, F., Lively, S., Pastrello, C., Tang, M., Lim, M., Pacheco, A., Qaiyum, Z., Yau, E., Baskurt, Z., Jurisica, I., Kapoor, M., Inman, R. D. Tags: ARD, Spondyloarthritis Source Type: research