RING induces cell cycle arrest and apoptosis in human breast cancer cells by regulating the HSF1/MT2A axis

In conclusion, RING1 suppressed the transcriptional activation of MT2A induced by HSF1 by facilitating the ubiquitination degradation of HSF1, resulting in cell cycle arrest and apoptosis in BC cells.PMID:37797799 | DOI:10.1016/j.yexcr.2023.113795

Source: Experimental Cell Research - October 5, 2023 Category: Cytology Authors: Di Liu Yize Guo Qin Du Yuxuan Zhu Ya Guo Source Type: research