The utility of salivary microRNA and proteins as potential diagnostic or prognostic biomarkers of concussion or mild traumatic brain injury: A systematic review

Introduction: Concussion or mild traumatic brain injury (mTBI) has become a major health concern with possible long-term clinical sequelae. Up to 50% of individuals with mTBI go unreported. At present there are no objective diagnostic or prognostic tools for concussion. Recently, emerging research in serum, cerebrospinal fluid and salivary biomarkers show promise as indicators of concussion. Saliva is the least invasive fluid for biomarker analysis. The aim of this systematic review was to examine the evidence for salivary microRNAs (miRNAs) and proteins in the diagnosis and prognosis of concussion.
Source: Journal of Science and Medicine in Sport - Category: Sports Medicine Authors: Tags: P2023SMA-246 Source Type: research