2-Geranyl-1-methoxyerythrabyssin II alleviates lipid accumulation and inflammation in hepatocytes through AMPK activation and AKT inhibition

In conclusion, GMET alleviated lipid accumulation and inflammation to preserve normal hepatocyte function in steatohepatitis. Thus, GMET is a novel potential multi-targeting compound to improve steatohepatitis.PMID:37782374 | DOI:10.1007/s12272-023-01464-z

Source: Archives of Pharmacal Research - October 2, 2023 Category: Drugs & Pharmacology Authors: Yiyuan Xi Soeun Kim Thi Thanh Thuy Nguyen Phil Jun Lee Jujia Zheng Zhuofeng Lin Namki Cho Source Type: research