LRRC23 deficiency causes male infertility with idiopathic asthenozoospermia by disrupting the assembly of radial spokes

This study provides strong preliminary evidence that LRRC23 defects are potential causative factors of AZS in humans, which expands our knowledge for improved genetic counseling and better reproductive recommendations for patients with AZS.PMID:37804054 | DOI:10.1111/cge.14433

Source: Clinical Genetics - October 7, 2023 Category: Genetics & Stem Cells Authors: Yuqian Li Qiang Zhang Qing Tan Xuan Sha Yang Gao Rong Hua Ping Zhou Zhaolian Wei Xiaojin He Yunxia Cao Tao Li Huan Wu Source Type: research