A current overview of the pharmacological composition of “La Chimique” consumed in Mayotte: Preliminary results of the CHASSE‐MAREE protocol

Mayotte Island, a French department, has for several years been faced with the consumption of a drug called “La Chimique.” The CHASSE-MAREE protocol aims to assess the composition of “La Chimique” products through successive sample collection campaigns. The first analytical results (80 samples collected in 2022) revealed that, as suspected, the main psychoactive constituents of this drug are SCRAs . This overview of SCRAs often includes associations and seems to vary from month to month and according to geographical location. AbstractMayotte Island, a French department located in the Mozambique Channel, has for several years been faced with the consumption of “La Chimique” (LC), reputed (but extremely poorly documented) to be a mixture of tobacco and synthetic cannabinoid receptor agonists (SCRAs). One of the objectives of the CHASSE-MAREE protocol is to assess the composition and heterogeneity of LC products through successive LC sample collection c ampaigns among users. Currently underway, we present here the first analytical results (samples collected in 2022). Between September and December 2022, 80 samples were collected throughout the island over three periods: 70 in the usual form of LC (small folded papers containing a plant-like sample, mostly tobacco), 6 powders, and 4 cigarettes. Analysis was performed using liquid chromatography with high-resolution mass spectrometry. The detected substances (number of detections) included SCRAs (MDMB-4en-PINACA [35], ...
Source: Drug Testing and Analysis - Category: Drugs & Pharmacology Authors: Tags: RESEARCH ARTICLE Source Type: research