The role of the kynurenine pathway in cognitive functioning after stroke: A prospective clinical study

The kynurenine pathway is the main metabolic pathway of tryptophan degradation and has been associated with stroke and impaired cognitive functioning, but studies on its role in post-stroke cognitive impairment (PSCI) are scarce. We aimed to investigate associations between metabolites of the kynurenine pathway at baseline and post-stroke cognitive functioning over time.

Source: Journal of the Neurological Sciences - October 3, 2023 Category: Neurology Authors: Lieke Bakker, Inez H.G.B. Ramakers, J.P.M. Eussen Simone, Kyonghwan Choe, Daniel L.A. van den Hove, Gunter Kenis, Bart P.F. Rutten, Robert J. van Oostenbrugge, Julie Staals, Arve Ulvik, Per M. Ueland, Frans R.J. Verhey, Sebastian K öhler Source Type: research