P127 Fat-fraction quantification using Dixon technique in Duchenne muscular dystrophy and its correlation with clinical progression and genotypic characteristics

Fat fraction quantification using Dixon technique is a relatively novel method that can be used to accurately quantify the extent of fatty infiltration in diseased muscle. While studies have found a correlation with muscle fat fraction (MFF) with disease severity in Duchenne muscular dystrophy (DMD), the current study additionally explores its correlation with the rate of functional decline in terms of MRC sumscore, North Star Ambulatory Assessment Score (NSAA), six-minute walk test (6MWT) and also with the disease genotype.

Source: Neuromuscular Disorders - October 1, 2023 Category: Neurology Authors: M. Mohanty, D. Menon, M. Kumar, A. Nalini, J. Saini, S. Vengalil, S. Nashi Tags: DMD - IMAGING AND OUTCOME MEASURES Source Type: research