Ambient Light Resistant Shortwave Infrared Fluorescence Imaging for Preclinical Tumor Delineation via the pH Low-Insertion Peptide Conjugated to Indocyanine Green

Conclusion: SWIRFI sensitivity and ambient light resistance enabled continued tracer clearance tracking with unparalleled SNR and CNR values at video rates for tumor delineation (achieving a tumor-to-muscle ratio above 20). In total, we provide a direct precedent for the democratic translation of an ambient light resistant SWIRFI and pHLIP ICG ecosystem, which can instantly improve tumor resection.

Source: Journal of Nuclear Medicine - October 3, 2023 Category: Nuclear Medicine Authors: Mc Larney, B. E., Kim, M., Roberts, S., Skubal, M., Hsu, H.-T., Ogirala, A., Pratt, E. C., Pillarsetty, N. V. K., Heller, D. A., Lewis, J. S., Grimm, J. Tags: Basic Science Investigations Source Type: research