Activation of Toll ‐like receptor 4 by thyroid hormone triggers abnormal B‐cell activation

ConclusionThe present study indicated that high levels of T3 can induce abnormal differentiation and activation of B cells by promoting TLR4 overexpression and provide novel insights into the roles of THs in the pathogenesis of GD.

Source: Immunity, Inflammation and Disease - September 29, 2023 Category: Allergy & Immunology Authors: Jie Wang, Guo ‐Qing Li, Shu Liu, Jing‐Jing Miao, Qi Sun, Wen‐Sha Gu, Xiao‐Ming Mao Tags: ORIGINAL ARTICLE Source Type: research