The clinical and immunological characteristics of COVID ‐19 patients with delayed SARS‐CoV‐2 virus clearance
ConclusionCDVC patients still have SARS-CoV-2 and these cases manifest with severe clinical symptoms due to persistent inflammation. Augmentation of the frequency of circulating Treg, severe lymphopenia, and functional exhaustion of T cells might lead to inefficient clearance of SARS-CoV-2. Therefore, enhancing lymphocyte counts and reversing T-cell exhaustion might be key methods to boost immune responses and eliminate SARS-CoV-2 in CDVC patients.
Source: Immunity, Inflammation and Disease - Category: Allergy & Immunology Authors: Jinsong Wang,
Debao Li,
Bo Tang,
Xuemin Sun,
Wenjiong Shi,
Hao Li,
Zhenhua Zhang,
Yuzhang Wu,
Yi Zhang,
Qinghua Qiao Tags: ORIGINAL ARTICLE Source Type: research
More News: Allergy & Immunology | Coronavirus | COVID-19 | Intensive Care | Outbreaks | Respiratory Medicine | SARS