Evaluation of the inhibitory effect of azoles on pharmacokinetics of lenvatinib in rats both in vivo and in vitro by UPLC ‐MS/MS

ConclusionIt is imperative to acknowledge the potential drug –drug interactions mediated by CYP3A4 between azoles and lenvatinib, as these interactions hold significant implications for their clinical utilization.

Source: Thoracic Cancer - September 29, 2023 Category: Cancer & Oncology Authors: Mengming Xia, Xueyi Song, Zebei Lu, Yu Wang, Quan Zhou, Peiwu Geng, Shuanghu Wang, Yunfang Zhou, Qingjun Wu, Aixia Han Tags: ORIGINAL ARTICLE Source Type: research