Effects and mechanisms of salidroside on the behavior of SPS-induced PTSD rats

In conclusion, our results demonstrated that Sal could attenuate SPS-induced PTSD-like behaviors by inhibiting hippocampal neuronal apoptosis, enhancing hippocampal synaptic plasticity, and reducing neuroinflammatory responses. These findings may provide a foundation for the potential clinical application of Sal in the treatment of PTSD.PMID:37742716 | DOI:10.1016/j.neuropharm.2023.109728

Source: Neuropharmacology - September 24, 2023 Category: Drugs & Pharmacology Authors: Xing-Dong Chen Jing-Xiang Wei Hai-Yan Wang Yu-Yuan Peng Can Tang Yang Ding Sen Li Zai-Yun Long Xiu-Min Lu Yong-Tang Wang Source Type: research