Po68

Data from the Focal Lesion Ablative Microboost in Prostate Cancer (FLAME) trial suggests a dose response for achieving local control of the dominant intraprostatic lesion (DIL). They reported a dose of ≥ 85 Gy achieves a 7-year probability of local control of almost 100%. Investigations using brachytherapy to microboost the DIL have been ongoing for decades and deliver a much higher dose than 85 Gy. Considering this, the purpose of this study is to perform a systematic review on brachytherapy mi croboost of the DIL to evaluate clinical outcomes and toxicities with this treatment approach.
Source: Brachytherapy - Category: Cancer & Oncology Authors: Source Type: research