EGR-1 Contributes to Pulmonary Edema by Regulating the Epithelial Sodium Channel in Lipopolysaccharide-Induced Acute Lung Injury

In conclusion, our study demonstrated that EGR-1 could promote pulmonary edema by downregulating ENaC-α at the transcriptional level in ALI. Our study provides a new potential therapeutic strategy for treatment of ALI.PMID:37732637 | DOI:10.1080/08820139.2023.2256778

Source: Immunological Investigations - September 21, 2023 Category: Allergy & Immunology Authors: Song Wang Jing Ma Xin Li Xinmiao Xian Guikun Tan Hongwei Cai Bingwu Yang Anqi Zhang Jianran Guo Guohao Gu Zhen Meng Bo Fu Source Type: research