Clinical features and mutational analysis of X-linked agammaglobulinemia patients in Malaysia

ConclusionThis report provides the first overview of demographic, clinical, immunological and genetic data of XLA in Malaysia. The combination of flow cytometric assessment and BTK genetic analysis provides a definitive diagnosis for XLA patients, especially with atypical clinical presentation. In addition, it may also allow carrier detection and assist in genetic counselling and prenatal diagnosis.
Source: Frontiers in Immunology - Category: Allergy & Immunology Source Type: research