High expression of Circ-PALLD in heart failure is transcriptionally regulated by the transcription factor GATA4

CONCLUSION: Circ-PALLD is highly expressed in heart failure and can be used as a novel molecular marker for chronic heart failure, and GATA4 may play important role in regulating its transcription. Circ-PALLD points a new direction for investigating the molecular mechanism of heart failure and may also serve as a potential therapeutic target for heart failure.PMID:37712274 | PMC:PMC10505580 | DOI:10.12122/j.issn.1673-4254.2023.08.14
Source: Journal of Southern Medical University - Category: Universities & Medical Training Authors: Source Type: research