Long-read sequencing reveals the landscape of aberrant alternative splicing and novel therapeutic target in colorectal cancer

ConclusionsThis data provides a rich resource for deeper studies of gastrointestinal malignancies. Newly identified splicing isoformTIMP1 Δ4-5 plays an important role in mediating CRC progression and may be a potential therapy target in CRC.
Source: Genome Medicine - Category: Genetics & Stem Cells Source Type: research