Genetic Screening of ZNF687 and PFN1 in a Paget ’s Disease of Bone Cohort Indicates an Important Role for the Nuclear Localization Signal of ZNF687

In conclusion, our findings support the involvement of genetic variation inZNF687 in the pathogenesis of classical PDB, thereby expanding its mutational spectrum.
Source: Calcified Tissue International - Category: Orthopaedics Source Type: research