Nanomaterials-based aptasensors: An efficient detection tool for heavy-metal and metalloid ions in environmental and biological samples

Environ Res. 2023 Sep 16:117170. doi: 10.1016/j.envres.2023.117170. Online ahead of print.ABSTRACTIn light of potential risks of heavy metal exposure, diverse aptasensors have been developed through the combination with nanomaterials for their timely and efficient detection in environmental and biological matrices. Aptamer-based sensors can benefit from multiple merits such as heightened sensitivity, facile production, uncomplicated operation, exceptional specificity, enhanced stability, low immunogenicity, and cost-effectiveness. This review highlights the capabilities of nanomaterial-based aptasensors for heavy metals based on their performance in terms of the basic quality assurance parameters (e.g., limit of detection, linear dynamic range, and response time). Out of covered studies, dendrimer/CdTe@CdS QDs-based ECL aptasensor was found as the most sensitive option with an LOD of 2.0 × 10-6 pM for Hg2+. The existing challenges in the nanomaterial-based aptasensors and their scientific solutions are also discussed.PMID:37722582 | DOI:10.1016/j.envres.2023.117170
Source: Environmental Research - Category: Environmental Health Authors: Source Type: research