Major Histocompatibility Class-I (MHC-I) downregulation in glioblastoma is a poor prognostic factor but not a predictive indicator for treatment failure

CONCLUSIONS: Glioblastoma with upregulated MHC-I showed a delayed tumor recurrence in comparison to those with downregulated MHC-I expression. However, downregulated MHC-I may not necessarily be an indicator of poor problems.PMID:37725880 | DOI:10.1016/j.prp.2023.154816

Source: Pathology, Research and Practice - September 19, 2023 Category: Pathology Authors: Nadeem S Butt Maher Kurdi Motaz M Fadul Sahar Hakamy Bassam M J Addas Eyad Faizo Shadi Alkhayyat Ahmed K Bamaga Taghreed Alsinani Yousef Katib Fahad Okel Yazid Maghrabi Abdulrahman J Sabbagh Rana Moshref Sultan Albalawi Alaa Alkhotani Fawaz Mohammed Nasse Source Type: research