Polyphyllin VII alleviates pulmonary hypertension by inducing miR-205-5p to target the β-catenin pathway

CONCLUSION: PP7 likely modulates β-catenin protein levels by promoting miR-205-5p expression, thereby alleviating PH, vascular remodeling and airway smooth muscle remodeling.PMID:37717533 | DOI:10.1016/j.biopha.2023.115516

Source: Biomedicine and pharmacotherapy = Biomedecine and pharmacotherapie - September 17, 2023 Category: Drugs & Pharmacology Authors: Fangyun Zhao Chunhong Pan Yue Zhang Jiao Yang Xiqian Xing Source Type: research