Effect of transplanted cells with CD184 and CD26 expressions and reconstitution of CD3+ lymphocyte population on long-term survival after autologous hematopoietic stem cell transplantation for multiple myeloma

Multiple myeloma (MM) is one of the most common hematological neoplasms. Its incidence is 4 per 100,000 persons [1,2]. Despite recent advances in medicine and the introduction of new drugs frequently targeting the causative mechanism, MM remains incurable. Autologous hematopoietic stem cell transplantation (auto-SCT) is still a standard procedure for responding patients with MM. Auto-SCT prolongs overall survival (OS) and progression-free survival (PFS) in patients with MM [3,4]. The median OS using modern therapies is an average of 6 years [2].
Source: Experimental Hematology - Category: Hematology Authors: Tags: Original Article Source Type: research