Improved phenotypic classification of male infertility to promote discovery of genetic causes

Nature Reviews Urology, Published online: 18 September 2023; doi:10.1038/s41585-023-00816-0In this Expert Recommendation, the authors provide a standardized nomenclature to improve the Human Phenotype Ontology tree with regard to the classification of non-syndromic male infertility. The implications of introducing this vocabulary in promoting communication across disciplines and institutions and in discovering novel genetic causes of non-syndromic male infertility are also discussed.

Source: Nature Reviews Urology - September 18, 2023 Category: Urology & Nephrology Authors: Margot J. Wyrwoll Godfried W. van der Heijden Csilla Krausz Kenneth I. Aston Sabine Kliesch Robert McLachlan Liliana Ramos Donald F. Conrad Moira K. O ’Bryan Joris A. Veltman Frank T üttelmann Source Type: research