Molecular docking analysis of the tumor protein beta arrestin-1 with oxadiazole compounds

Bioinformation. 2023 Jan 31;19(1):111-116. doi: 10.6026/97320630019111. eCollection 2023.ABSTRACTBeta arrestins are a family of adaptor proteins that help in the regulation of signaling and trafficking of various G protein coupled receptors (GPCRs). Six oxadiazole derivatives taken from literature are analyzed for anti-cancer properties. The toxicity profiles of all the drugs were similar to Tamoxifen used as control. Data shows that compounds 2, 4, and 6 exhibited comparably significant molecular interactions with the cancerous protein for further consideration.PMID:37720289 | PMC:PMC10504516 | DOI:10.6026/97320630019111

Source: Cancer Control - September 18, 2023 Category: Cancer & Oncology Authors: Vipra Sharma Gayathri Rengasamy Surya Sekaran Kavitha Sankaran Vishnu Priya Veeraraghavan Rajalakshmanan Eswaramoorthy Source Type: research