Knocking down SOX2 overcomes the resistance of prostate cancer to castration via notch signaling

CONCLUSION: We demonstrated that SOX2/Notch signaling was responsible for Enzalutamide resistance in CRPC. Targeting SOX2/Notch signaling might represent a new choice for the treatment and therapy of CRPC.PMID:37716921 | DOI:10.1007/s11033-023-08757-y
Source: Mol Biol Cell - Category: Molecular Biology Authors: Source Type: research