Calculation of initial effective bolus dose of phenylephrine for treatment of post-spinal hypotension in patients with pre-eclampsia undergoing caesarean section: a non-randomised controlled trial

Pre-eclampsia is a hypertensive disorder associated with increased maternal and fetal morbidity and mortality.1 In pre-eclampsia, post-spinal hypotension is less common and less severe,2,3 however if it occurs, especially for more than two minutes, it can exacerbate the adverse effects on the fetus by affecting uteroplacental blood flow and increasing oxygen free radicals in the fetoplacental circulation.4 The mother can also have nausea, vomiting, dizziness or cardiovascular instability, so prompt treatment of hypotension is important for good maternal and neonatal outcomes.
Source: International Journal of Obstetric Anesthesia - Category: Anesthesiology Authors: Tags: Original Article Source Type: research