Factors of Central Lymph Node Metastasis in Papillary Thyroid Cancer Based on C-TIRADS Analysis
Horm Metab Res 2023; 55: 585-591 DOI: 10.1055/a-2142-4811To study risk factors for central lymph node metastasis (CLNM) in papillary
thyroid cancer (PTC) using the Chinese Thyroid Imaging Reporting and Data System
(C-TIRADS). We retrospectively analysed patients who underwent PTC surgery and
central lymph node dissection at First People’s Hospital of Foshan City.
The clinical and ultrasonic data of the patients from 1150 cases were analysed
by multivariate regression to evaluate the correlation between grayscale
ultrasound (US) features, C-TIRADS score, and the classification of thyroid
nodules and CLNM of PTCs. The C-TIRADS score was 3.0±1.0 in the CLNM
group, which was higher than that in the non-CLNM group (p<0.001). Sex
(male) (OR=1.586, 95% CI 1.232–2.042, p<0.001),
age (≤45 years) (OR=1.508, 95% CI 1.184–1.919,
p=0.001), location of nodes (lower pole) (OR=2.193, 95%
CI 1.519–3.166, p<0.001), number (multifocal) (OR=2.204,
95% CI 1.227–2.378, p<0.001), microcalcification
(OR=1.610, 95% CI 2.225–4.434, p=0.002),
extrathyroidal extension (OR=2.204, 95% CI 1.941–3.843,
p<0.001), maximum diameter of nodule (≥20 mm)
(OR=3.211, 95% CI 2.337–4.411, p<0.001), and
C-TIRADS score (OR=1.356, 95% CI 1.204–1.527,
p<0.001) were PTC in independent risk f...
Source: Hormone and Metabolic Research - Category: Endocrinology Authors: Huang, Weijun Chen, Deli Zhong, Minying Ye, Jieyi Zhi, Zhiyuan Xiao, Yanyan Zhong, Yuan Tags: Original Article: Endocrine Care Source Type: research
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