Multilevel visuomotor control of locomotion in Drosophila

Curr Opin Neurobiol. 2023 Aug 29;82:102774. doi: 10.1016/j.conb.2023.102774. Online ahead of print.ABSTRACTVision is critical for the control of locomotion, but the underlying neural mechanisms by which visuomotor circuits contribute to the movement of the body through space are yet not well understood. Locomotion engages multiple control systems, forming distinct interacting "control levels" driven by the activity of distributed and overlapping circuits. Therefore, a comprehensive understanding of the mechanisms underlying locomotion control requires the consideration of all control levels and their necessary coordination. Due to their small size and the wide availability of experimental tools, Drosophila has become an important model system to study this coordination. Traditionally, insect locomotion has been divided into studying either the biomechanics and local control of limbs, or navigation and course control. However, recent developments in tracking techniques, and physiological and genetic tools in Drosophila have prompted researchers to examine multilevel control coordination in flight and walking.PMID:37651855 | DOI:10.1016/j.conb.2023.102774

Source: Current Opinion in Neurobiology - August 31, 2023 Category: Neurology Authors: Tom ás L Cruz M Eugenia Chiappe Source Type: research