Pyroptosis of chondrocytes activated by synovial inflammation accelerates TMJ osteoarthritis cartilage degeneration via ROS/NLRP3 signaling

CONCLUSION: Our findings offer novel insight into the role of synovial inflammation-induced chondrocyte pyroptosis in promoting cartilage degradation during TMJ-OA via the ROS and NLRP3 signaling pathway.PMID:37625369 | DOI:10.1016/j.intimp.2023.110781

Source: International Immunopharmacology - August 25, 2023 Category: Allergy & Immunology Authors: Xin Liu Yanyan Li Jie Zhao Zhihui Hu Wei Fang Jin Ke Wei Li Xing Long Source Type: research