Multi-dimensional metabolomic profiling reveals dysregulated ornithine metabolism hallmarks associated with a severe acute pancreatitis phenotype

CONCLUSIONS: The plasma metabolome of AP patients is distinctive, which shows promise for early SAP diagnosis. AP aggravation is linked to the activated ornithine metabolic pathway and its inadequate levels of catabolites in in-situ lesion.PMID:37619665 | DOI:10.1016/j.trsl.2023.08.003

Source: Translational Research : the journal of laboratory and clinical medicine - August 24, 2023 Category: Laboratory Medicine Authors: Jinxi Yang Na Shi Shisheng Wang Manjiangcuo Wang Yan Huang Yiqin Wang Ge Liang Juqin Yang Juan Rong Yun Ma Lan Li Ping Zhu Chenxia Han Tao Jin Hao Yang Wei Huang Daniel Raftery Qing Xia Dan Du Source Type: research