Considerations for pooling real-world data as a comparator cohort to a single arm trial: a simulation study on assessment of heterogeneity
Novel precision medicine therapeutics target increasingly granular, genomically-defined populations. Rare sub-groups make it challenging to study within a clinical trial or single real-world data (RWD) source;...
Source: BMC Medical Research Methodology - Category: Research Authors: Daniel Backenroth, Trevor Royce, Jose Pinheiro, Meghna Samant and Olivier Humblet Tags: Research article Source Type: research