Triggering pyroptosis enhances the antitumor efficacy of PARP inhibitors in prostate cancer

ConclusionOur findings highlight a novel therapeutic strategy for enhancing the long-term response to olaparib beyond HRR-deficient tumors in PCa, underscoring the critical role of GSDME in regulating tumorigenesis.
Source: Cellular Oncology - Category: Cancer & Oncology Source Type: research