TDP-43-regulated cryptic RNAs accumulate in Alzheimer ’s disease brains

Inclusions of TAR DNA-binding protein 43 kDa (TDP-43) has been designated limbic-predominant, age-related TDP-43 encephalopathy (LATE), with or without co-occurrence of Alzheimer ’s disease (AD). Approximately,...

Source: Molecular Neurodegeneration - August 21, 2023 Category: Neurology Authors: Virginia Estades Ayuso, Sarah Pickles, Tiffany Todd, Mei Yue, Karen Jansen-West, Yuping Song, Jes ús González Bejarano, Bailey Rawlinson, Michael DeTure, Neill R. Graff-Radford, Bradley F. Boeve, David S. Knopman, Ronald C. Petersen, Dennis W. Dickson, Tags: Research article Source Type: research