Changes in hospital consumption of opioid and non-opioid analgesics after colorectal endometriosis surgery

AbstractThe aim of this study was to analyze postoperative consumption of analgesics during hospitalization following colorectal surgery for endometriosis. We conducted a retrospective study at Tenon University Hospital, Paris, France from February 2019 to December 2021. One hundred sixty-two patients underwent colorectal surgery: eighty-nine (55%) by robotic and seventy-three (45%) by conventional laparoscopy. The type of procedure had an impact on acetaminophen and nefopam consumed per day: consumption for colorectal shaving, discoid resection, and segmental resection was, respectively, 2(0.5), 2.1(0.6), 2.4(0.6) g/day (p = 10–3), and 25(7), 30(14), 31(11) mg/day (p = 0.03). The total amount of tramadol consumed was greater following robotic surgery compared with conventional laparoscopy (322(222) mg vs 242(292) mg,p = 0.04). We observed a switch in analgesic consumption over the years: tramadol was used by 70% of patients in 2019 but only by 7.1% in 2021 (p <  10–3); conversely, ketoprofen was not used in 2019, but was consumed by 57% of patients in 2021 (p <  10–3). A history of abdominal surgery (OR = 0.37 (0.16–0.78,p = 0.011) and having surgery in 2020 rather than in 2019 (OR = 0.10 (0.04–0.24,p <  10–3)) and in 2021 than in 2019 (OR  = 0.08 (0.03–0.20,p <  10–3)) were the only variables independently associated with the risk of opioid use. We found that neither clinical characteristics nor intraop...
Source: Journal of Robotic Surgery - Category: Surgery Source Type: research