Fractional Flow Reserve-Guided PCI or Coronary Bypass Surgery for 3-Vessel Coronary Artery Disease: 3-Year Follow-Up of the FAME 3 Trial

CONCLUSIONS: At 3-year follow-up, there was no difference in the incidence of the composite of death, MI, or stroke after FFR-guided PCI with current-generation drug-eluting stents compared with CABG. There was a higher incidence of MI after PCI compared with CABG, with no difference in death or stroke. These results provide contemporary data to allow improved shared decision-making between physicians and patients with 3-vessel coronary artery disease.REGISTRATION: URL: https://www.CLINICALTRIALS: gov; Unique identifier: NCT02100722.PMID:37602376 | DOI:10.1161/CIRCULATIONAHA.123.065770

Source: Circulation - August 21, 2023 Category: Cardiology Authors: Frederik M Zimmermann Victoria Y Ding Nico H J Pijls Zsolt Piroth Albert H M van Straten Laszlo Szekely Giedrius Davidavicius Gintaras Kalinauskas Samer Mansour Rajesh Kharbanda Nikolaos Östlund-Papadogeorgos Adel Aminian Keith G Oldroyd Nawwar Al-Attar Source Type: research