The dose-dependent effect of estrogen on bone mineral density in trans girls

CONCLUSION: Higher estrogen dosage is associated with a greater increase in lumbar spine BMD Z-scores. Increasing dosage up to 2mg estradiol is insufficient to optimize BMD and approximately 4 mg may be required for adequate serum concentrations.PMID:37590955 | DOI:10.1093/ejendo/lvad116
Source: European Journal of Endocrinology - Category: Endocrinology Authors: Source Type: research