Multicenter, retrospective registry of isolated atherosclerotic popliteal arteries treated with endovascular revascularization

This study aimed to investigate the efficacy of endovascular therapy (EVT) using the newer devices for IAPLs. This retrospective multicenter registry analyzed patients with lower extremity artery disease having IAPLs who underwent EVT using the newer devices between 2018 and 2021. The primary outcome was primary patency 1  year after EVT. A total of 392 consecutive patients undergoing EVT for IAPLs were enrolled. The Kaplan–Meier analysis showed that the primary patency and the freedom from target lesion revascularization were 80.9% and 87.8% 1 year after EVT, respectively. The multivariate Cox proportional hazar ds regression analysis showed that the clinical features that were independently associated with restenosis risk were drug-coated balloon (DCB) use for younger age (<  75 years old; adjusted hazard ratio, 3.08 [95% confidence interval 1.08–8.74];P = 0.035), non-ambulatory status (2.74 [95% confidence interval 1.56–4.81];P <  0.001), cilostazol use (0.51 [95% confidence interval 0.29–0.88];P = 0.015), severe calcification (1.86 [95% confidence interval 1.18–2.94];P = 0.007), and small external elastic membrane (EEM) area measured by intravascular ultrasound (IVUS) (<  30 mm2) (2.07 [95% confidence interval 1.19 –3.60];P = 0.010). From the univariate analysis, among patients treated with DCB, younger patients (n = 141) were associated with more comorbidities including smoking (P <  0.001), diabetes mellitus (P...
Source: Heart and Vessels - Category: Cardiology Source Type: research