Liver Transplant for Intrahepatic Cholangiocarcinoma
Intrahepatic cholangiocarcinoma (iCCA) tends to be asymptomatic until late stages, leading most of the patients to present at advanced stages of the disease. A combination of medical and surgical therapy is crucial for patient management. Historically, poor outcomes resulted in liver transplantation being formally contraindicated for patients with iCCA; however, recent advances in patient selection and neoadjuvant therapy have resulted in a paradigm shift in liver transplant oncology. As a result, the feasibility of liver transplantation for iCCA is being reevaluated by several centers as a therapeutic alternative for select patients with locally advanced unresectable disease.
Source: Surgical Clinics of North America - Category: Surgery Authors: Olanrewaju A. Eletta, Guergana G. Panayotova, Keri E. Lunsford Source Type: research
More News: Bile Duct Cancer | Cancer & Oncology | Cholangiocarcinoma | Liver | Liver Transplant | Neoadjuvant Therapy | Surgery | Transplant Surgery | Transplants | Urology & Nephrology