Is synovitis inevitable after ACL injury?

Synovitis is now well recognized as being a part of the pathophysiology of posttraumatic osteoarthritis (PTOA). Chronic synovial inflammation that does not resolve is not only well-documented in clinical imaging and histopathological studies of OA and PTOA, but is now also associated with driving joint pain and the multifaceted disease processes in the joint. In the setting of anterior cruciate ligament (ACL) rupture, a major risk factor for PTOA development, surgical reconstruction of the ACL results in long-term restoration of joint stability with overwhelmingly positive patient-reported outcomes and a high degree of patient satisfaction.
Source: Osteoarthritis and Cartilage - Category: Rheumatology Authors: Tags: Editorial Source Type: research