TMEM106B aggregation in neurodegenerative diseases: linking genetics to function

Mutations of the gene TMEM106B are risk factors for diverse neurodegenerative diseases. Previous understanding of the underlying mechanism focused on the impairment of lysosome biogenesis caused by TMEM106B loss-...

Source: Molecular Neurodegeneration - August 10, 2023 Category: Neurology Authors: Hai-Shan Jiao, Peng Yuan and Jin-Tai Yu Tags: Review Source Type: research