Specific detection of tau seeding activity in Alzheimer ’s disease using rationally designed biosensor cells

The prion-like propagation of tau in neurodegenerative disorders implies that misfolded pathological tau can recruit the normal protein and template its aggregation. Here, we report the methods for the develop...

Source: Molecular Neurodegeneration - August 8, 2023 Category: Neurology Authors: Aurelien Lathuiliere, Youhwa Jo, Romain Perbet, Cameron Donahue, Caitlin Commins, No é Quittot, Zhanyun Fan, Rachel E. Bennett and Bradley T. Hyman Tags: Methodology Source Type: research