Viruses, Vol. 15, Pages 1707: Seroprevalence of IgG Antibodies Directed against Dengue, Chikungunya and West Nile Viruses and Associated Risk Factors in Madagascar, 2011 to 2013
Viruses, Vol. 15, Pages 1707: Seroprevalence of IgG Antibodies Directed against Dengue, Chikungunya and West Nile Viruses and Associated Risk Factors in Madagascar, 2011 to 2013
Viruses doi: 10.3390/v15081707
Authors:
Anaïs Broban
Marie-Marie Olive
Michael Luciano Tantely
Anne-Claire Dorsemans
Fanjasoa Rakotomanana
Jean-Pierre Ravalohery
Christophe Rogier
Jean-Michel Heraud
Soa Fy Andriamandimby
Arboviruses have been shown to circulate in Madagascar, including West Nile, dengue, and chikungunya viruses, though the extent of their circulation remains poorly documented. We estimated the seroprevalence of these three arboviruses in Madagascar and determined risk factors associated with seropositivity. Serum samples obtained from 1680 individuals surrounding the Sentinel Health Centers network in all regions of the country were analyzed using ELISA and hemagglutination inhibition assays for dengue, chikungunya, and West Nile viruses IgG antibodies, and multivariate logistic regression models were run. Overall, 6.5% [IC 95% 3.2–9.9] were seropositive for dengue virus, predominantly of Dengue serotype 1, 13.7% [IC 95% 6.5–20.9] for chikungunya virus, and 12.7% [IC 95% 9.0–16.5] for West Nile virus. There was no association with age, showing that dengue and chikungunya viruses were likely recently introduced. Eastern and Northern parts were more affected by dengue and chikungunya viruses, while West Nile virus seemed...
Source: Viruses - Category: Virology Authors: Ana ïs Broban Marie-Marie Olive Michael Luciano Tantely Anne-Claire Dorsemans Fanjasoa Rakotomanana Jean-Pierre Ravalohery Christophe Rogier Jean-Michel Heraud Soa Fy Andriamandimby Tags: Article Source Type: research