Parkinson's disease and related conditions

Parkinson's disease (PD) is a common neurodegenerative condition, affecting 2 –3% of individuals>65 years of age. It is characterized by a loss of dopaminergic neurons in the midbrain leading to a movement disorder encompassing bradykinesia, rest tremor, rigidity and postural stability. However patients also experience a range of non-motor symptoms, reflecting more widespread pathology in the peripheral and autonomic nervous systems as well as the brainstem and cortex. Some non-motor symptoms emerge years before motor problems.
Source: Medicine - Category: Internal Medicine Authors: Tags: Movement disorders Source Type: research