Sequential Chromogenic IHC: Spatial Analysis of Lymph Nodes Identifies Contact Interactions between Plasmacytoid Dendritic Cells and Plasmablasts

We present a comprehensive guide for developing customized biomarker panels to investigate cell-cell interactions in the context of immune responses in cancer. This approach revealed novel contact interactions between plasmablasts and plasmacytoid dendritic cells in lymph nodes from patients with head and neck cancer.PMID:37484199 | PMC:PMC10361537 | DOI:10.1158/2767-9764.CRC-23-0102

Source: Cell Research - July 24, 2023 Category: Cytology Authors: Natalie Claudio My-Tien Nguyen Adrian Wanner Ferdinando Pucci Source Type: research