The prognostic and predictive role of tumor-infiltrating lymphocytes (FoxP3  + and CD8 +) and tumor-associated macrophages in early HER2 + breast cancer

ConclusionIn the HER2  + Luminal B subgroup, high FoxP3 + TILs were associated with shorter DFS. A high CD8 + mTILs/CD68 + TAMs ratio seems to associate with impressive efficacy of trastuzumab.
Source: Breast Cancer Research and Treatment - Category: Cancer & Oncology Source Type: research