Rifampin urinary excretion to predict serum targets in children with tuberculosis: a prospective diagnostic accuracy study

Conclusions
Urine spectrophotometry correlated with a clinically relevant serum target for rifampin, representing a step toward personalised dosing for children in TB-endemic settings.

Source: Archives of Disease in Childhood - July 19, 2023 Category: Pediatrics Authors: Thomas, T. A., Lukumay, S., Yu, S., Rao, P., Siemiatkowska, A., Kagan, L., Augustino, D., Mejan, P., Mosha, R., Handler, D., Petros de Guex, K., Mmbaga, B., Pfaeffle, H., Reiss, R., Peloquin, C. A., Vinnard, C., Mduma, E., Xie, Y. L., Heysell, S. K. Tags: ADC Global child health Source Type: research