Prognostic and Clinical Significance of Human Leukocyte Antigen Class I Expression in Breast Cancer: A Meta-Analysis

ConclusionThis meta-analysis demonstrated that enhanced HLA class I protein expression is significantly  associated with the better DFS of patients with breast cancer, especially TNBC, as well as with ER and PR negativity, HER2 positivity, TNBC, and high Ki-67 indices and nuclear grades. The immune target HLA class I may serve as a prognostic indicator for breast cancer.
Source: Molecular Diagnosis and Therapy - Category: Molecular Biology Source Type: research